Myo I, II and V

The nature of the myosin tail determines what it binds to and therefore what it does. Myo I binds membranes and is involved in endocytosis. Myo II forms dimers that associate to each other in a bidirectionally symmetrical configuration to give rise to a myosin II bouquet. Myo V dimerises but does not form large complexes - but binds via adaptor molecules to vesicles (for organelle transport/positioning), microtubules (to direct cell polarity) and RNA (for cell differentiation)