Microtubule associated proteins (MAPs) : regulators of microtubule (MT) stability and function

Plus end microtubule binding proteins (+TIPS): EB-1 Only binds GTP-tubulin - stabilises the MT seam. DASH ring complex - Binds polymerising and depolymerising MTs (couples kinetochore movement to MT depolymerisation). Cross-linking, stabilising or bundling proteins: MAP2, Tau - Binds side and stabilizes parallel MTs. MAP65 (Ase1) - Binds side and stabilizes anti-parallel MTs