B. Gastrointestinal (GI): Atropine

Gastrointestinal (GI): Atropine (as the active isomer, l-hyoscyamine) can be used as an antispasmodic to reduce activity of the GI tract. Atropine and scopolamine are probably the most potent drugs available that produce this effect. Although gastric motility is reduced, hydrochloric acid production is not significantly affected. Thus, the drug is not effective in promoting healing of peptic ulcer. In addition, doses of atropine that reduce spasms also reduce saliva secretion, ocular accommodation, and micturition (urination). These effects decrease patient compliance with the use of these medications