Bracketing can be applied to studies with multiple STRENGTHS of identical or closely related formulations. Examples include but are not limited to: __

(1) capsules of different strengths made with different fill plug sizes from the same powder blend (2) tablets of different strengths manufactured by compressing varying amounts of the same granulation (3) oral solutions of different strengths with formulations that differ only in minor excipients (e.g., colorants, flavorings)