Dam1/DASH complex

The Dam1/DASH complex is a fungal specific heterodecamer which is necessary for kinetochore-microtubule interaction in budding yeast. The purified heterodecameric complex is T-shaped and can link together to form chains. In vitro the complex can form rings around purified microtubules. The ring is composed of 16 heterodecamers with a gap of 75 A between the outside of the microtubule and the inside of the ring.