TRNA structure (cloverleaf shape)

TRNAs are named according to the amino acid with which they become charged. Isoaccepting tRNAs: several different tRNAs become charged with the same amino acid. The aminoacyl-tRNA synthetases show specificity for the tRNAs they charge, and the correct interaction is with cognate tRNAs. tRNA contains a number of modified nucleosides.