Opioid addiction treatment

Methadone - potent Mu agonist - orally = slow absorption, long lasting, slow release, no euphoria. Misused to achieve euphoria LAAM - potent Mu agonist - orally 3x per week Buprenorphine - partial agonist - reduces withdrawal - orally 3x per day. Misused Suboxone - combines buprenorphine and naloxone - sublingual or buccal (dissolved in mouth) - naloxone deterrent prevents misuse - if taken orally naloxone results in immediate withdrawal symptoms