asthma drugs: - ACh not good at crossing bio membranes because it is permanently positively charged.
- atropine has an ester bond and a nitrogen that can become protonated and bind to mAChR. But in its uncharged form it can cross bio membranes easily

Question

- ACh not good at crossing bio membranes because it is permanently positively charged. 
- atropine has an ester bond and a nitrogen that can become protonated and bind to mAChR. But in its uncharged form it can cross bio membranes easily

georgia reeves · Accepted Answer

structural differences between atropine and acetylcholine

asthma drugs

- ACh not good at crossing bio membranes because it is permanently positively charged. - atropine has an ester bond and a nitrogen that can become protonated and bind to mAChR. But in its uncharged form it can cross bio membranes easily

Structural differences between atropine and acetylcholine

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