Buscar
Estás en modo de exploración. debe iniciar sesión para usar MEMORY

   Inicia sesión para empezar

level: Easy

Questions and Answers List

level questions: Easy

QuestionAnswer
normal WBC count5-10 K/uL
syndrome caused by developmental failure of the 3rd and 4th pharyngeal pouchDi George Syndrome
Also known as kissing diseaseInfectious Mononucleosis
Most common pathogen in kissing diseaseEBV
T-cell hyperplasia in kissing disease occurs in what part of the lymph nodeparacortex
T-cell hyperplasia in kissing disease occurs in what part of the spleen?periarterial lymphatic sheath
Test used for screening of kissing diseaseMonospot test
A negative monospot test is suggestive of what kissing diseae etiology?CMV
Monospot test turns positive within how many weeks after infection?1 week
What cell is in the picture?Atypical lymphocyte
Dormancy of virus in B cells leads to an increased risk for recurrence and what?B-cell lymphoma
defined as the accumulation of >20% blasts n the bone marrowLeukemia
large immature cells with punched out nucleoliBlasts
Lymphoblasts have a positive nuclear staining for what?TdT
Most common type of ALLB-ALL
usually presents n teenagers as mediastinal (thymic) massacute lymphoblastic lymphoma
neoplastic accumulation of myeloblasts (>20%) in the bone marrowAcute myeloid leukemia
Myeloblasts are usually characterized by positive cytoplasmic staining for what?Myeloperoxidase (MPO)
Crystal aggregates of MPO may be seen as what?Auer rods
subtype of AML which involves translocation of the retinoic acid receptorAcute promyelocytic leukemia
treatment for APLall-trans-retinoic acid (ATRA)
subtype of AML wherein monoblasts prolferates and usually lacks MPOAcute monocytic leukemia
subtype of AML wherein megakaryoblasts proliferates and usually lacks MPOAcute megakaryoblastic anemia
Blasts characteristically inflitrate what part of the body in acute monocytic anemia?Gums
most common leukemia overallChronic Lymphocytic Leukemia (CLL)
Neoplastic proliferation of mature B-cells characterized by hairy cytoplasmic processesHairy Cell Leukemia
accumulation of hairy cells occurs in what part of the spleen?Red pulp
associated with HTLV-1Adult T-cell Leukemia/Lymphoma (ATLL)
radiologic finding in ATLLlytic (punched-out) bone lesions
neoplastic proliferation of mature CD4 T-cells in the epidermisMycosis fungoides
aggregates of neoplastic cells in the epidermisPautrier microabscesses
neoplastic proliferation of mature cells of the myeloid lineageMyeloproliferative disoders
neoplastic proliferation of mature myeloid cells especially granulocytes and their precursorsChronic Myeloid Leukemia (CML)
Basophils are characteristically increased in this diseaseChronic Myeloid Leukemia (CML)
What fraction of CML can transform to AML?two-thirds
What fraction of CML can transform to ALL?one-third
neoplastic proliferation of mature myeloid cells especially RBCsPolycythemia Vera (PV)
First line treatment in PVphlebotomy
second-line treatment in PVhydroxyurea
neoplastic proliferation of lymphoid cells that forms a massLymphoma
two major types of LymphomaHodgkin Lymphoma (HL) and Non-Hodgkin lymphoma (NHL)
malignant cells of HLReed-Sternberg cells
overall frequency of NHL60%
overall frequency of HL40%
malignant cells of NHLLymphoid cells
age group of NHLLate adulthood
age group of HLYoung adults
spread of NHLdiffuse; often extranodal
spread of HLcontiguous; rarely extranodal
neoplastic proliferation of small B cells (CD20) that form follicle-like nodulesFollicular lymphoma
neoplastic proliferation of small B cells (CD20) that expands the mantle zoneMantle cell lymphoma
region immidately adjacent to lymph node folliclesMantle zone
neoplastic proliferaton of small B cells (CD20) that expands the marginal zoneMarignal zone lymphoma
region immidately adjacent to lymph node mantle zoneMarginal zone
marginal zone lymphoma in mucosal sitesMALToma
neoplastic proliferation of intermediate-sized B cells (CD20) associated with EBVBurkitt lymphoma
characteristiic finding of Burkitt lymphoma under microscopystarry-sky apperance
most common form of NHLDiffuse Large B-cell Lymphoma
neoplastic proliferatoin of large B cells (CD 20) that grow diffusely in sheetsDiffuse Large B-cell Lymphoma
large B cells with multilobed nuclei and prominent nucleoliReed-Sternberg cells
most common type of HLNodular sclerosis
most common demographics of nodular sclerosisyoung adult female
subtype of HL that has the best prognosisLymphocyte-rich
this HL subtype is characterized by abundant eosinophiilsMixed cellularity
most aggressvie subtype of HL usually seen in the elderly and HIV positivie individualsLymphocyte-depleted
Malignant proliferation of plasma cells in the bone marrowMultiple myeloma
Most common primary malignancy of the boneMultiple myeloma
Most common malignant lesion of the bone overallMetastasis
Most common cause of death in multiple myelomainfection
free light chain excreted in the urine of patients with multiple myelomaBence Jones protein