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level: Moderate

Questions and Answers List

level questions: Moderate

QuestionAnswer
Normal hemoglobin levels in males13.5mg-17.5 mg/dL
Normal hemoglobin levels in females12.5-16.0 mg/dL
Normocytic MCV values80-100 um^3
Laboratory measure of iron in the bloodSerum Iron
Laboratory measure of transferrin molecules in the bloodTotal Iron-binding capacity
Laboratory percentage of transferrin molecules that are bound by iron% saturation
normal value of % saturation33%
reflects iron stores in macrophages and liverSerum Ferritin
syndrome characterized by iron deficiency anemia with esophageal web and atrophic glossitisPlummer-Vinson Syndrome
co-factor of Aminolevulinic acid synthethase (ALAS)vitamin B6
enzyme that catalyzes the conversion of ALA to porphobilinogenAminolevulinic acid dehydrogenase (ALAD)
enzyme that attaches protoporphyrin to iron to make hemeFerrocheletase
chromosome that codes for globin alpha geneschromosome 16
tetramers of β chains that damage RBCs when 3 alpha genes are deletedHbH
tetrameres of γ chains that damage RBCs in utero when 4 alpha genes are deletedHb Barts
chromosome that codes for globin beta geneschromosome 11
Folate circulates in the serum in what form?methyltetrahydrofolate
Methyl THF tranfers its methyl group of what molecule?Vitamin B12 or Cobalamin
This molecule receives methyl from Vitamin B12homocysteine
adding methyl to homocystein produces what moleculemethionine
impaired division of granulocytic precursors leads to what kind of neutrophils?hypersegemented neutrophils
parasite that causes damage to the terminal ileum which may then lead to vitamin B12 deficiencyDiphyllobothrium latum
cofactor tor the conversion of methylmalonic acid to succinyl CoAVitamin B12 or Cobalamin
Two main causes of normocytic anemiaperipheral destruction and underproduction
normal reticulocyte count1-2%
corrected reticulocyte count formulaRC x Hct/45
indicates good marrow responsecorrected RC >3%
indicates poor marrow responsecorrected RC <3%