| TOXICITIES PHENYTOIN | • Nystagmus (Dancing Eyeball)
• Diplopia & Ataxia (most common dose- related adverse effects)
• Sedation
• Gingival Hyperplasia
• Hirsutism
• Coarsening of facial features with mild
peripheral neuropathy
• Osteomalacia
• Megaloblastic anemia |
| TOXICITIES CARBAMAZEPINE | • Diplopia
•Ataxia |
| TOXICITIES PRIMIDONE | • similar to those of phenobarbital
• drowsiness occurs early in the
treatment and if the initial dose is
too large |
| Toxicities VIGABATRIN | • drowsiness
• dizziness
• weight gain
• agitation
• confusion
• psychosis
• visual field defects |
| Toxicities LAMOTRIGINE | • Dizziness
• Headache
• Diplopia
• Rash |
| Toxicities FELBAMATE | • Aplastic anemia
• Severe hepatitis |
| Adverse Effects GABAPENTIN | • Somnolence
• Dizziness
• Ataxia
• Headache
• Tremor |
| Toxicities PREGABALIN | • Somnolence
• Dizziness
• Ataxia |
| Adverse Effects LACOSAMIDE | • Dizziness
• Headache
• Nausea
• Diplopia |
| Adverse Effects LEVETIRACETAM | • Somnolence
• Asthenia
• Ataxia
• Dizziness
• Agitation or Anxiety |
| Adverse Effects TIAGABINE | • Nervousness, dizziness, tremor,
difficulty in concentrating, depression
(minor)
• Excessive confusion, somnolence,
ataxia (may require discontinuation)
• Seizures and psychosis |
| Adverse Effects TOPIRAMATE | • Somnolence, fatigue, dizziness, cognitive slowing, paresthesias, nervousness, confusion
• Acute myopia & glaucoma
• Teratogenic
• Urolithiasis |
| Adverse Effects ZONISAMIDE | • Drowsiness
• Cognitive impairment
• Potentially serious skin
rashes |
| Toxicities ETHOSUXIMIDE | • Gastric distress (pain, N&V)
• Transient lethargy or fatigue
• Headache
• Dizziness
• Hiccup
• Euphoria |
| Toxicities SODIUM VALPROATE | • N &V, abdominal pain, heartburn
• Weight gain, increased appetite, hair
loss
• Hepatotoxicity
• Thrombocytopenia
• SPINA BIFIDA
• CV, orofacial, digital abnormalities |
