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Index
»
PHARMACOLOGY 1
»
Chapter 2
»
Level 1
level: Level 1
Questions and Answers List
level questions: Level 1
Question
Answer
describes the actions of a drug on the body and the influence of drug concentrations on the magnitude of the response
PHARMACODYNAMICS
the component of a cell or organism that interacts with a drug and initiates the chain of events leading to the drug's observed effects
RECEPTOR
• Their ligands are presently unknown • May prove useful targets for the development of new drugs.
ORPHAN RECEPTORS
• MEDIATE the actions of endogenous chemical signals such as neurotransmitters, autacoids and hormones.
REGULATORY PROTEINS
• also identified as drug receptors • may be inhibited or activated by binding a drug • Ex: dihydrofolate reductase for methotrexate
ENZYMES
membrane receptor for digitalis glycosides a TRANSPORT PROTEIN
Na+/K+ ATPase Pump
RECEPTOR FOR COLCHICINE Involved in Mitosis Structural Protein
Tubulin
receptors which are spare for a given pharmacologic response that are able to possibly elicit a maximal biologic response at a concentration of agonist that does not result in occupancy of the full complement of available receptors
SPARE RECEPTORS