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level: Level 1

Questions and Answers List

level questions: Level 1

QuestionAnswer
NAEGLERIA FOWLERI is a free living Amoeba found in?Distributed world wide, they are found in soil, lakes, brackish water, hot springs, heated swimming pools.
NAEGLERIA FOWLERI is an organism that alternated between Amoebic form and flagellated form, which form is found in tissue?Amoebic form is found in tissue.
contraction of NAEGLERIA FOWLERI?they gain entry via nasal mucosa during swimming, travel along the olfactory nerve and gain entry to the brain via the cribiform plate.
clinical disease caused byNAEGLERIA FOWLERI?PAM
NAEGLERIA FOWLERI cause PAM where cases are fetal, symptoms include?headaches, fever, rigid neck, mental confusion coma and eventually death.
the life cycle of NAEGLERIA FOWLERI1)cyst in water, 2) trophozoite dvelops, may becomem flagellated, 3)divide by binary division, promitosis, 4) penetration of nasal mucosa, 5) migrate olfactory nerve to the brain
NAEGLERIA FOWLERI divides by binary division with nuclear membrane intect, the process is known aspromitosis
the diagnostic stage of NAEGLERIA FOWLERI?trophozoite in csf and brain tissue, flagellated form occasionally in csf
the 3 stages in the life cycle of NAEGLERIA FOWLERIcyst, trophozoite and the flagellated forms
which of the stages in the life cycle of NAEGLERIA FOWLERI will most likely be found in the environment?the cyst.
an individual went for a swim in a hot spring: a) what is the causative agent of the t disease he may contract? b) what is the disease ? c) what symptoms may develop in 1-2 days ? d) and within 9 days?a)NAEGLERIA FOWLERI. b) PAM c) headaches, fever, nausea and vomiting d) meningeo-encephalitis, irrational behavior, coma leading to death
diagnosis of this disease is usually during autopsy where csf show motile organism.PAM caused by NAEGLERIA FOWLERI
NAEGLERIA FOWLERI can be cultured onnon-nutrient agar containing bacteria
which form of NAEGLERIA FOWLERI will be found in a) period of low nutrition? b) prolonged adverse condition?a) flagellated form, b) cyst
a young boy read about diseases contracted from the environment. He is particularly concerned about contracting PAM. he seeks your advice as a 3rd year medical student about the least likely place to contract this disease. a) where b) why?a) sea water b)NAEGLERIA FOWLERI is sensitive to chlorine
staining of csf sample being screened for NAEGLERIA FOWLERI can be done with?H&E, Giemsa-Wright stain
lab diagnosis of NAEGLERIA FOWLERIwet mount, CT and MRI of head, staining, fluorescent antibody immunofluorescent, indirect immunofluorescent
the pathology of PAMHemmorhage and Nercrosis. mainly in the frontal cortex.
case 1a) you are a 3rd year medical student present at an autopsy of an individual who died app 9 days after attending a pool party and swimming in a heated swimming pool. the pathologist tells you she sees Hemorrhage and necrosis. which part of the brain is most likely involved? which disease is suspected?the frontal cortex. PAM
case 1b) in a public health discussion about case 1a) what preventative measure would you suggest and why?treat swimming pools with chlorine since NAEGLERIA FOWLERI, the causative agent of PAM is susceptible to chlorine.
in treating an infection with NAEGLERIA FOWLERI which medication is used?AMPHOTERIUM B, MICONAZOLE AND RIFAMPIN ( wellz., administered how?)