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level: rheumatology and connective tissue disease

Questions and Answers List

level questions: rheumatology and connective tissue disease

QuestionAnswer
What can be a secondary condition of arthiritisSecondary sjogren’s syndrome
What oral implication can arthiritis havePeriodontitits
Tx of arthrititsNSAIDs Disease-modifying antirheumatic drugs (e.g. methotrexate) Steroids Biologic therapies (e.g. anti-TNF therapy) Destructive effects of TNF
TNF MABsAdalimumab Infliximab
Uveitis:inflammatory of the uveal tract (blue layer)
Tx of arthritisNSAIDs Disease modifying anti-rheumatic drugs, e.g. methotrexate for psoriatic arthritis (PsA) Steroids Biological therapies (e.g. anti-TNF therapy)
SLE patients present withHair loss oral ulcerations and connnective tissue disease vasculitits
RaynaudsBlood vessels narrow reducing flow to hands which become cold and white
livedo reticularisMottles reticules vascular pattern that appears like a lace purplish discolouration of the lower extremities
Scleroderma affectsSkin thickening Difficulty opening mouth Raynaud’s phenomenon Internal organ disease: Lungs Kidney Gut
Skin changes in sclerodermaInflammatory Indurative than atrophic phase Oedema Tightening Thickening Waxy feel Loss of function in hands, arms, legs Chest involvement Telangectasia
Vasculitits describeTemperotal arteritis or giant cell ateritis (GCA) Prevalence 200/100,000 aged >50 Headache Scalp tenderness Jaw claudication Fatigue Visual loss
Granulomatosis with polyangiitis (GPA) (Wegeners) is-Bloody nasal discharge Nasal collapse Stridor Cough and haemoptysis Renal involvement
Pagets disease- describemaxilla more than mandible can cause hypercementosis- tx with bisphosphonates
What two drugs can cause MRONJBisphosphonates and denosomab
TMJ pain can be caused byOA RA Ankylosing spondylitis and psoriatic arthritis Juvenile idiopathic arthritis ( up to 50% of children with polyarticular disease)
Mouth ulcers can be caused byArthridites- reactive arthritis
Connective tissue diseases and vasculitidesBehcets disease SLE