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level: Non malignant haematology

Questions and Answers List

level questions: Non malignant haematology

QuestionAnswer
What does warfarin blockvitamin K epoxide reductase
What do patients need to be given when they first start taking warfarinanother anticoagulant
Antidote to warfarinVitamin K if non emergency
Most important factor in intrinsic and extrinsic pathwayFactor X
Which drug potentiates the natural affect of antithrombinHeparin
How is heparin effectiveness measuredAPTT
What type of drug is heparinIV
anti-Xa drugs(Rivaroxaban, Apixaban and Edoxaban)
and the direct thrombin inhibitorsDabigatran
what is IdarucizumabMops up dabigatron
What may make INR unstableliver disease, alcoholism, renal failure, on antiplatelet drugs
What should you tell DOAC taking patients to do before a non invasive procedurenot take DOAC in the morning
what does tranexamic acid doprevent breakdown of a blood clot
Where are clotting factors madein the liver
What does desmopressin docause the body to release more vWNF
Drugs that reduce platelet functionaspirin, dipyridamole and clopidogrel.
What should you do if someoene is on 2 antiplatelet drugsConsult haemoolosit
Bernard Soulier Sydrome, Glanzmann’s Thrombasthaenia and Grey platelet syndrome what are thesehereditary platelet dysfunction syndromes
Acquired platelet defects□ Acquired ◊ Antiplatelet drugs: aspirin, clipidogrel, dipyridamole ◊ Other drugs: anti-epileptics, chemotherapy ◊ Autoimmune: ITP Bone marrow failure: leukaemia, aplastic anaemia
Symtom of mild anaemiaBurning mouth
Symtom of severe aneamiaTongue losing filliform appearance
What is pllummer vinson syndromeWebbing of oesophagus and tongue dystrophy leads to dysphagia
haemoglobinopathy isis when not enough red blood cells are being made/ not properly made
Low b12 can cause□ Peripheral neuropathy □ Spinal cord dysfunction □ Optic atrophy Neurocognitive impairment
Renal disease anaemia treated with whatEPO
What is this describing- when the body makes autoantibodies to intrinsic factor which binds B12pernicous anaemia
B12 deficiency can present in the mouth asGlossitis