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level: Lecture 20: Immunopathology

Questions and Answers List

level questions: Lecture 20: Immunopathology

QuestionAnswer
What does Immunopathology mean?It's a pathology subspecialty that deal with the immune responses associated with diseases.
What is a "hypersensitivity reaction?"They are undesirable reactions produced by the NORMAL immune system
What is an antigen?Any substance that triggers the immune system to produce an antibody.
What is an antibody?It is a PROTEIN produced by the immune system when it is exposed to antigens.
What is an "Immune Complex"It is a molecule generated by binding an: - antigen + antibody - antigen + antigen - antibody + complement
Exposure to what triggers a Type I (Anaphylactic Type) Hypersensitivity Reaction?An Antigen
True or False: Type I (Anaphylactic Type) Hypersensitivity Reactions are always fatal?False. Not always. (They should probably consider seeing a doctor, regardless)
Characterizes a Type II Hypersensitivity Reaction (Antibody – Mediated Type)?A hypersensitivity reaction characterized by the production of an antibody in directed at a specific cell or tissue.
After a blood transfusion, a patient has a reaction. What kind or type of hypersensitivity reaction is it?Type II Hypersensitivity Reaction (Antibody – Mediated Type)
What characterizes a Type III Hypersensitivity Reaction (Immune Complex Disease)?an abnormal immune response mediated by the formation of antigen-antibody aggregates called "immune complexes." (which deposit in tissues, resulting inflammation and tissue injury)
Systemic lupus erthematosus (SLE) and Rheumatoid arthritis (RA) are both diseases that concern various tissues in the body. They also often have what kind/type of hypersensitivity reactions?Type III Hypersensitivity Reaction (or, "Immune Complex Disease")
What characterizes a Type IV Hypersensitivity Reaction (Delayed Typed or Cell-Mediated)?A hypersensitivity reaction mediated by sensitized T lymphocytes (white blood cells).
Graft rejection occurs when the recipient's immune system attacks the donated graft and begins destroying the transplanted tissue or organ. What kind/type of hypersensitivity reaction is this?Type IV Hypersensitivity Reaction (Delayed Typed or Cell-Mediated)
What is Systemic Lupus Erythematosus?Systemic Lupus Erythematosus is an autoimmune disease in which the immune system attacks its own tissues, (causing widespread inflammation and tissue damage in the affected organs).