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Infection of Circulatory System


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[Front]


Aside from cardiovascular, circulatory system also include what?
[Back]


Lymphatic system (lymph nodes, tonsils, thymus, spleen)

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Infection of Circulatory System - Marcador

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Infection of Circulatory System - Detalles

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Aside from cardiovascular, circulatory system also include what?
Lymphatic system (lymph nodes, tonsils, thymus, spleen)
Aside from cardiovascular, circulatory system also include what?
Lymphatic system (lymph nodes, tonsils, thymus, spleen)
Does bacteria fight with blood?
No, because there's a lot of WBC in the bloodstream
Aside from cardiovascular, circulatory system also include what?
Lymphatic system (lymph nodes, tonsils, thymus, spleen)
What is septicemia?
An overwhelm body defenses
Is bacteremia and septicemia the same?
Yes, but not in all instance.
What kind of instance does bacteremia and septicemia is different from each other?
When our body is immunocompromised (aids, hiv), because the bacteria present in the blood overwhelm body defenses cause our immune system is weak that's why our body can't fight and the bacteria starts to divide.
What is lymphadenopathy?
A disease in lymph nodes
What kind of nature is rickettsial and ehrlichial?
Zoonotic in nature (which means it came from animals and passed to humans)
Spotted fever rickettsiosis is formerly known as?
Rocky Mountain spotted fever (RMFS)
Person with Rocky Mountain spotted fever experience?
- moderate to high fever - extreme exhaustion (prostation) - muscle pain - sever headache - chills -conjunctival infection -maculopapular rash on extremities (palms, soles, and much body) on about third day. - In about 4 days, small purplish areas (petechiae) develop as a result of bleeding in the skin
What country does Rocky Mountain spotted fever occur?
US especially the atlantic seaboard.
What kind of pathogen is rickettsia rickettsil?
- Gram negative - obligate intracellular pathogen
Is Rickettsia rickettsil invade the cell? and why?
Yes, because they need to live inside the cell to multiply or propogate.
What kind of cell does rickettsia rickettsil invade?
Endothelial cells (cells that line blood vessels)
How to diagnose Ricketssia Rickettsil?
- through Cells - Immunodiagnostic procedures.
Reservoirs and Mode of transmission of Rickettsia Rickettsil?
Reservoirs: ticks on dogs, rodents and other animals. Transmission: Bite of infected tick. person to person transmission rarely occurs through blood transfusion.
What is endemic typhus fever?
Acute febrile disease that is similar but milder than epidemic typhus.
Symptons include in Endemic Typhus fever?
Shaking chills headache fever faint pink rash
What is the other term for Endemic Typhus fever?
Murine typhus fever and flea-borne typhus
Is endemic typhus fever have case here in the pH?
Yes, especially in province and farmers
What kind of bacteria is Rickettsia typhi?
- Gram negative bacterium -obligate intracellular pathogen
Reservoirs and Mode of Transmission of Rickettsia Typhi?
Reservoirs: Rats, mice, possibly other mammals, and infected rat fleas. Transmission: occurs from rat to flea to human. (infected fleas defecate while feeding)
What kind of instances does Rickettsia typhi transmit from human?
Through bite wound or other superficial abrasions.
How to diagnose Rickettsia Typhi?
It can be culture by using cell. -Immunodiagnotic procedure to try find the antigens and antibodies within the patients sample to look for the present of Rickettsia Typhi to confirm the presence of type of species
What is Epidemic Typhus Fever?
Is also known as Louse born typhus is an acute rickettsial disease
Patient with Epidemic Typhus fever experienced?
Sudden onset of headache, chills, prostration, fever, and general pains. Rash appears on the fifth or sixth day, initally on the upper trunk, followed by spred to the entire body but usually not to the face, palms, or soles/
Is epidemic typhus fever fatal?
Yes if it is not treated.
Where does epidemic typhus fever or louse-borne typhus occurs?
In areas where people live under unhygienic conditions and are louse infested.
What kind of bacteria is rickettsia prowazekki?
A gram negative bacterium and obligate intracellular pathogen.
Reservoirs and Mode of Transmission of Epidemic Typhus Fever?
Reservoirs: Infected humans and body lice (Pediculus humanus) Transmission: Human to louse to human through bite wound or other superficial abrasions.
How to diagnose Epidemic Typhus Fever?
- Cell can be culture. - Immunodiagnostic procedures.
What is Ehrlichiosis?
Acute, febrile illness ranging from asymptomatic to mild to sever and life threatening conditions?
Symptoms associated with ehrlichiosis?
Acute influenza like illnes with fever, headache and generalized malaise.
Ehrlichiosis is reminiscent of what infection?
Spotted fever rickettsiosis but without a rash.
What are the two types of ehrlichiosis?
Human monocytic ehrlichiosis and human granulocytic anaplasmosis.
Where does HGA more occurs?
In southeast and mid- atlantic states
Where does HME more occurs?
In states with high rates of lyme disease particulary connecticut, minnesota, New york and wisconsin.
What kind of tick is similar with HGA?
A tick that transmit BORRELIA BURGDORFERI.
What is the causitive agent of ehrlichiosis?
Ehrlichia chaffeensis causing HME and Anaplasma phagocytophilum causing HGA.
Reservoirs and Mode of Transmission of Ehrlichiosis?
Reservoirs: unknown Transmission: tick bite The two different types of ehrlichiosis seem to be different types of species.
What is Brucellosis?
Disease of the reticuloendothelial system. It have a prolonged incubation period.
Symptoms that occurs in brucellosis?
Non specific complaints. - fever - sweats - arthralgias -myalgia - fatigue -loss of appetite -weight loss -hepatomegaly -splenomegaly
What are the different species of brucella that are commonly involved in human infections?
Brucella melitensis, Brucella albortus, Brucella auis, brucella spp.
What kind of bacteria is brucella?
Gram negatice coccobacilli.
Reservoirs and mode of transmission of brucellosis
Reservoirs: zoonotic disease (can be found on animals) Mode of Transmission: Consumption of contaminated food like goat milk cheese, direct contact ith infected animals (goats, cattle or sheep)
How to diagnose Brucella?
It is recovered most often in blood or bone marrow cultures, becauwse brucella spp are considered potential agents of bioterrorism, full identification should be performed at public health lab using MOLECULAR baswed methods. SEROLOGIC methods can also aid in the diagnosis.
What is Lyme Disease?
Also known as lyme borrelosis is a tick borne disease
3 stages of lyme disease
1: early - distinctivem target liked, reds skin lesions usually at the site of the tick bite, expanding to 15cm in diameter. 2: it include fatigue, chills, fever, headache, stiffneck, muscle pain, joint aches with or without lymphadenopathy 3: neurologic abnormalties (aseptic meningitis, facial paralysis, myelitis, and encephalitis)) and cardiac abnormalities (arrhytmia and pericarditis)) sseveral weeks poor or months after the intial symptoms appear.
Where does lyme disease get its name?
From Us, Lyme connecticut.
Where does lyme disease usually occur?
North east and upper midwest.
What kind of bacteria is borrelia burgdorferi?
Lossely coiled Gram negative spirochete.
Reservoirs and Mode of transmission of Borrelia burgdorferi?
Reservoirs: ticks, rodents (especially deer mice), and mammals (especially deer) Transmission: Occurs via tick bite, Person 2 person transmission does not occur
How to diagnose borrelia burgdorferi?
By observation of the characteristics target like skin lesions, plus immunodiagniostic and molecular diagnostic procuders.
Borrelia burgdorferi can be grown on a what?
Special medium (barbour-stoenner-kelley) medium at 33 Celcius although yield from patient specimen is not high
What is plague?
An acute, often sever zoonosis.
What are the symptoms occurs in Plague?
Fever, chills, malaise, myalgia, nausea, prostration, sore throat and headache.
What is bubonic plague?
Swollen, inflamed, and tender lymph nodes (buboes) that develop.
Pnuemonic plague is?
Highly communicable. involves the lungs. It can result outbreaks or devastating epidemics.
Septicemic plague is?
May lead to spetic shock, meningitis and death
What kind of bacteria is yersinia pestis?
Non-motile, bipolar-staining, gram negative coccobacillus
Reservoirs and mode of transmission of Yersinia pestis.
Reservoirs: Rodents (especially ground squirrels in the US), fleas, rarely rabbits, wild carnivores, and domestic cats. MOT: flea bite (from rodent to flea to human), handling tissues of infected rodents, rabbits, and other animals, droplet transmissions from person to person (pneumonic plague)
How to diagnose Yersinia pestis?
By observation of the typical appearnce of Yersinia Pestis, (bipolar-staining bacilli that resemble safety pins) in gram stained or wwright gernsa-stained sputum, cerebrospinal fluid, or material aspirated from a bubo. Diagnosis can also be made by culture. Molecular based methods.
What is tularemia?
Rabbit fever, zoonoic in nature, with variety of clinical manifestations, depending on the portal entry of pathogen into the body.
Where does tularemia mostly present?
In skin ulcer and regional lymphadenitis.
What is the result of ingestion of tularemia?
Pharyngitis, abdominal pain, diarrhea, and vomiting.
Fatality rate of tularemia
30-60% fatality rate.
Etiologic agent of tularemia?
Francisella tularensis
What kind of bacteria is franciscella tularensis?
A pleomorphic gram negative coccobacillus, some strains are more virulent than others.
Reservoirs and MOT of tularemia?
Reservoirs: Wild animals (especiallyh in rabbits, muskrats, beavers. and some domestic animals and hard ticks. MOT: tick bite, ingestion of contaminated meat or drinking water, entry of organism into a wound while skinning infected animals, inhalation of dust, or animal bites. Person to person does not occur.