Controlling Gene Expression
🇬🇧
In Inglés
In Inglés
Practique preguntas conocidas
Manténgase al día con sus preguntas pendientes
Completa 5 preguntas para habilitar la práctica
Exámenes
Examen: pon a prueba tus habilidades
Pon a prueba tus habilidades en el modo de examen
Aprenda nuevas preguntas
Modos dinámicos
InteligenteMezcla inteligente de todos los modos
PersonalizadoUtilice la configuración para ponderar los modos dinámicos
Modo manual [beta]
Seleccione sus propios tipos de preguntas y respuestas
Modos específicos
Aprende con fichas
Completa la oración
Escuchar y deletrearOrtografía: escribe lo que escuchas
elección múltipleModo de elección múltiple
Expresión oralResponde con voz
Expresión oral y comprensión auditivaPractica la pronunciación
EscrituraModo de solo escritura
Controlling Gene Expression - Marcador
Controlling Gene Expression - Detalles
Niveles:
Preguntas:
20 preguntas
| 🇬🇧 | 🇬🇧 |
| What does a mutagenic agent such as high energy ionising radiation do? | It can increase the rate of mutation |
| What effect does a deletion, addition, or duplication have on the DNA base sequence? | Produce a frame shift. |
| What are totipotent stem cells? | Cells that have the ability to differentiate into any type of cell. |
| How are pluripotent stem cells different from totipotent stem cells? | They can differentiate into all cells apart from those of the placenta |
| What is the source of totipotent stem cells? | Human embryos |
| What are iPS cells? | Induced pluripotent Stem Cells that have been genetically engineered from unipotent stem cells. |
| What is transcription? | The first stage of protein synthesis in which messenger RNA is produced from an exposed DNA sense strand. |
| What is the complex of proteins called that induce transcription after the move into the nucleus from the cytoplasm. | Transcription Factors |
| What enables the transcription factor to bind to the correct region of DNA? | A complementary binding site. |
| The presence of the female hormone oestrogen can enter a cell and instigate transcription - how does it enter the cell? | As it is a lipid-soluble, steroid hormone, it can easily diffuse through the phospholipid bi-layer of the plasma membrane. |
| When an oestrogen molecule binds to a TF, what happens to effectively "switch-on" transcription? | The binding site will change shape to make it complementary to the specific region of DNA so transcription can commence. |
| A DNA-Histone complex forms chromatin i.e. "unraveled" DNA. in the cell nucleus. What are histones? | Proteins |
| What is the result of increased acetylation of histone proteins? | Looser, less condensed DNA with easer access to DNA for transcription factors. |
| What is the result of increased Methylation of DNA? | Tighter, more condensed DNA with reduced access to DNA for transcription factors. |
| As epigenetic changes can activate or silence specific genes, it follows that the protein enzymes that are key in methylation and acetylation provide a potential target for drug development. How could increased methylation result in tumour development | Increased methylation could result in reduced activity of tumour suppressor gene, leading to increased, uncontrolled cell division. |