PHARMACOLOGY 1: • an amino acid, an analog of GABA
• ORIGINALLY PLANNED AS
SPASMOLYTIC

• ADJUCT against PARTIAL SEIZURES
AND GENERALIZED TONIC-CLONIC
SEIZURES
• POSTHERPETIC NEURALGIA

MOA: decreases excitatory
transmission by acting on
VG Ca2+ channels
presynaptically

Question

• an amino acid, an analog of  GABA
• ORIGINALLY PLANNED AS 
SPASMOLYTIC

• ADJUCT against PARTIAL SEIZURES 
AND GENERALIZED TONIC-CLONIC 
SEIZURES
• POSTHERPETIC NEURALGIA

MOA: decreases excitatory 
transmission by acting on 
VG Ca2+ channels 
presynaptically

LEIGHTON DWIGHT OBILLOS · Accepted Answer

GABAPENTIN
• Neurontin®

• an amino acid, an analog of GABA • ORIGINALLY PLANNED AS SPASMOLYTIC • ADJUCT against PARTIAL SEIZURES AND GENERALIZED TONIC-CLONIC SEIZURES • POSTHERPETIC NEURALGIA MOA: decreases excitatory transmission by acting on VG Ca2+ channels presynaptically