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level: Level 9 - TABLET COATING

Questions and Answers List

level questions: Level 9 - TABLET COATING

QuestionAnswer
 INVOLVES SUCCESSIVE APPLICATIONS OF SUCROSE BASE SOLUTION to the tablet course in a suitable coating equipment  MORE PREFERRABLE THAN FILM COATINGSugar coating
Sugar coating STEPS1) Sealing: a separate care from water, through sealing we can make the tablet a water proofing tablet 2) Sub-coating: contour the tablets rapidly and its size and mixing the gelatin and acacia 3) Syruping: syrup coating of sucrose base solution on drying phase 4) Finishing: coloring of tablets in three to four coats 5) Polishing: done to canvas polishing wax solution 6) Printing: for identification purpose with special edible inks
 There Is a DEPOSITION usually by a SPRAY METHOD  USE A THIN FILM OF POLYMER TO SURROUND A TABLET COAT  INCLUDES THE POLYMER, PLASTICIZER, COLORANT, SOLVENT  As a RESULT, will have a LIGHTER TABLET compared to sugar coated tabletsFilm coating
Problems in film coating:1 Blistering 2 Wrinkling 3 Bridging 4 Sweating 5 Orange peel 6 Flaking 7 Bloom and spotting
1 causes REDUCE ADHESION BETWEEN THE FILMS and surface due to RAPID DRYING (bubble formation) 2 due to IMPROPER DRYING or FILM FORMER DEFECT1 Blistering 2 Wrinkling (PROBLEMS IN FILM COATING)
1 bridging of monogram present in the tablet core 2 PRESENCE of the OILY FILMS and DROPLETS OF LIQUID in the film surface due to incompatibility1 Bridging 2 Sweating
1 ROUGHNESS IN THE SURFACE because of PREMATURE DRYING of anatomize droplets of solution or STRAINING TWO VISCOUS COATING SOLUTION 2 due to RAPID DRYING BETWEEN the COATS 3 due to the CONDITION of MIGRATION of PLASTICIZER TO SURFACES1 Orange peel 2 Flaking 3 Bloom and spotting (PROBLEMS IN FILM COATING)
TABLET COATING Other new concepts:A. Electrostatic coating B. Laminated coating El La
 employed to APPLY FILMS TO CONDUCTIVE MATERIALS by IMPARTING AN IONIC CHARGE to the SUBSTRATE; an OPPOSITE CHARGE to the COATING MATERIALS  ENSURE as THIN & CONTINUOUS FILM ON THE SURFACEA. electrostatic coating
 PROVIDES A SECOND ACTION OR LAYER OF MEDICAMENT for the TABLET then it is USED AS CIRCUIT ACTION TABLET, ENTERIC or BUCCAL TABLETB. Laminated coating
BASIC PROCESSES used in Application of coating:1. Pan coating 2. Air suspension coating 3. Dip coating 4. Tablet compression coating PAD T
 A PROCESS in which USED IN A BULK SUGAR AND FILM COATING  MOSTLY USED IN THE INDUSTRYPan coating
 MOST DEPENDABLE METHOD in applying film coat  Ex. Fluidized bed coaterAir suspension coating
 MATERIALS TO BE COATED are usually PLACED IN THE BASKETS & DIP in the CONTAINERS of a COATED SOLUTIONSDip coating
 It is DONE BY THE SPECIAL DOSAGE FORM  If you want to MAKE A TABLET FROM TWO INCOMPATIBLE DRUGS  The two incompatible drugs may be separated by placing one in the core and in the coatingTablet compression coating